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Neurohypophysial hormones of the 1‐month‐old bovine fetus: Absence of vasotocin during mammal development
Author(s) -
Rouille Y.,
Levy B.,
Chauvet M.T.,
Chauvet J.,
Acher R.
Publication year - 1988
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(88)80113-3
Subject(s) - vasotocin , vasopressin , fetus , oxytocin , endocrinology , medicine , hormone , biology , neuropeptide , arginine , peptide hormone , chemistry , pregnancy , biochemistry , receptor , amino acid , genetics
The neurohypophysial hormones of the 1‐month‐old bovine fetus have been identified by their positions in ion‐exchange chromatography and their retention times in high‐pressure reverse‐phase partition chromatography. Arginine vasopressin and oxytocin have been recognized. The molar ratio vasopressin/oxytocin in neurohypophysis is about 6 in the 1‐month‐old fetus compared with 4 in the 3‐month‐old fetus, 2.7 in the 7‐month‐old fetus and 1 in the adult. Vasotocin is virtually absent even in the early fetus (less than 0.1% of arginine vasopressin). The occurrence of a vasotocin gene expressed in the fetus but silent in the adult appears unlikely.