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Counteraction by 20‐hydroxyecdysone of the effect of juvenile hormone on phosphorylation of ribosomal protein S6
Author(s) -
Itoh Kohji,
Ueno Kohji,
Natori Shunji
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)81469-2
Subject(s) - 20 hydroxyecdysone , juvenile hormone , ecdysone , phosphorylation , ribosomal protein s6 , juvenile , hormone , medicine , biology , ecdysterone , flesh fly , endocrinology , protein phosphorylation , microbiology and biotechnology , larva , botany , protein kinase a , genetics
Phosphorylation of ribosomal protein S6, induced when the fat body of Sarcophaga peregrina (flesh‐fly) larvae was incubated in vitro in the presence of 32 P, was found to be suppressed by juvenile hormone. This suppressive effect of juvenile hormone was counteracted by a physiological concentration of 20‐hydroxyecdysone. Since 20‐hydroxyecdysone is known to induce phosphorylation of S6 in vivo, this reaction was suggested to be regulated by the balance of the effects of ecdysone and juvenile hormone.