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Identification of disulfide bonds in carboxy‐terminal propeptides of human type I procollagen
Author(s) -
Koivu Juha
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)81350-9
Subject(s) - procollagen peptidase , disulfide bond , protein precursor , identification (biology) , terminal (telecommunication) , chemistry , biochemistry , amino terminal , stereochemistry , peptide sequence , microbiology and biotechnology , biology , computer science , enzyme , gene , telecommunications , botany
Intra‐chain and inter‐chain disulfide bonds within the carboxy‐terminal propeptides of human type I procollagen were studied using cyanogen bromide cleavage of the propeptides and electrophoresis on SDS‐polyacrylamide/glycerol gels. The results could provide a better understanding of the assembly of proα‐chains into procollagen.