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Molecular cloning of cDNA coding for human PGP 9.5 protein
Author(s) -
Day Ian N.M.,
Thompson R.J.
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)81327-3
Subject(s) - complementary dna , polyadenylation , coding region , biology , microbiology and biotechnology , cloning (programming) , molecular cloning , nucleic acid sequence , signal peptide , protein sequencing , genetics , peptide sequence , messenger rna , gene , computer science , programming language
The co‐ordinate sequencing of the human neuronal and neuroendocrine marker protein PGP 9.5 and its cDNA is described. The cDNA encodes the complete protein (212 amino acids), and the 340 nucleotide 3'‐noncoding region including the polyadenylation signal, indicating an mRNA slightly larger than 1 kb in size. Protein sequencing of 50% of PGP 9.5 confirms the deduced protein sequence.