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Oestrogen‐induced expression of oncogenes in the immature rat uterus
Author(s) -
Travers Maureen T.,
Knowler John T.
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)81267-x
Subject(s) - uterus , endocrinology , messenger rna , administration (probate law) , medicine , polyadenylation , hormone , expression (computer science) , andrology , biology , chemistry , gene , genetics , political science , computer science , law , programming language
4 h after a single precocious administration of oestrogen there was a considerable but short‐lived surge in the uterine levels of myc ‐encoded polyadenylated mRNA. This was followed by a further peak 28 h after hormone administration. The expression of ras Ha showed a totally different time course with a build up of hybridizable message that peaked 8 h after oestrogen administration.