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Voltage gating in porin channels
Author(s) -
Lakey Jeremy H.
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)81262-0
Subject(s) - porin , gating , biophysics , membrane , ion channel , chemistry , membrane potential , bacterial outer membrane , bilayer , biology , biochemistry , escherichia coli , receptor , gene
Data from experiments in which porin channels are reconstituted into planar bilayer membranes are reviewed for their relevance to porin channel gating in vivo. Contradictory evidence concerning voltage gating indicates that the different results may stem from the variety of purification techniques employed. The likelihood of voltage gating as a property of E. coli porins in vivo is discussed in relation to the possible magnitude of the membrane potential across tho outer membrane.