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The influence of the chain length of aldehydes on the fluorescence of chromolipids
Author(s) -
Montfoort A.,
Bezstarosti K.,
Groh M.M.J.,
Koster J.F.
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)80559-8
Subject(s) - malondialdehyde , phosphatidylethanolamine , fluorescence , chemistry , incubation , liposome , chromatography , fluorescence anisotropy , biochemistry , biophysics , phospholipid , membrane , phosphatidylcholine , biology , oxidative stress , physics , quantum mechanics
Incubation of phosphatidylethanolamine containing liposomes with malondialdehyde and other aldehydes with different chain lengths results in the fluorescence of chromolipids. Relative to malondialdehyde, the fluorescence was greatly enhanced with increasing chain length upon incubation of 2‐alkenals with phospholipids. Similar results were found using the total lipid extracted from erythrocyte ghosts. It seems that the hydrophobic character of the aldehydes is important for the amount of fluorescence detected in lipid bilayers.