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Induction of protein synthesis in response to ultraviolet light, nalidixic acid and heat shock in the cyanobacterium Phormidium laminosum
Author(s) -
Nicholson Paul,
Osborn Rupert W.,
Howe Christopher J.
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)80362-9
Subject(s) - nalidixic acid , thermophile , heat shock protein , dna , biochemistry , chemistry , protein biosynthesis , dna synthesis , biology , microbiology and biotechnology , biophysics , escherichia coli , enzyme , gene
Synthesis of three polypeptides (43, 34 and 26 kDa) was enhanced or induced in the thermophilic cyanobacterium Phormidium laminosum following irradiation with UV light. Synthesis of several polypeptides was also enhanced/induced following treatment with nalidixic acid. Three had similar molecular masses to those induced by UV. One of these (43 kDa) was also apparently enhanced following prolonged heat shock, as were a number of other polypeptides with a wide range of molecular masses. The specific induction of the 34 and 26 kDa polypeptides following DNA damage and inhibition of replication suggests that they may be involved in DNA repair and, possibly, also in recombination.