Premium
Isolation and characterization of a lectin with exclusive specificity towards mannose from snowdrop ( Galanthus nivalis ) bulbs
Author(s) -
Van Damme Els J.M.,
Allen Anthony K.,
Peumans Willy J.
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)80129-1
Subject(s) - isolation (microbiology) , lectin , mannose , biology , mannan binding lectin , botany , biochemistry , microbiology and biotechnology
A lectin was isolated from snowdrop ( Galanthus nivalis ) bulbs by affinity chromatography on mannoseagarose. It is a tetrameric protein composed of 4 identical subunits of 13 kDa which are not held together by disulphide bridges. The G. nivalis agglutinin exhibits exclusive specificity towards mannose. Although it readily agglutinates rabbit erythrocytes it is completely inactive with human red blood cells.