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Enhanced metabolism of phosphatidylinositol in Candida tropicalis in association with filamentous growth caused by ethanol
Author(s) -
Uejima Yasuhide,
Koga Teiichiro,
Kamihara Teijiro
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)80026-1
Subject(s) - phosphatidylinositol , ethanol , inositol , candida tropicalis , metabolism , yeast , biochemistry , chemistry , ethanol content , signal transduction , receptor
Candida tropicalis Pk 233 grows in filamentous form in ethanol‐supplemented medium, and myo ‐inositol prevents the ethanol ettect [(1979) Bioch!em. Biophys. Res. Commun. 91, 351–355]. Cells, which were grown with ethanol to the log phase, exhibited an increased rate of phosphatidylinositol turnover as judged by pulse‐chase experiments with 32 P i . Such enhanced metabolism of phosphatidylinositol was not observed in fully developed filamentous cells at the stationary phase or in yeast‐like cells which were grown without added ethanol or with ethanol plus myo ‐inositol. The metabolism of other phospholipids was not affected by ethanol.