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Fecal excretion of intestinal glycosphingolipids by newborns and young children
Author(s) -
Larson Göran,
Watsfeldt Peter,
Falk Per,
Leffler Hakon,
Koprowski Hilary
Publication year - 1987
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(87)80009-1
Subject(s) - lactosylceramide , feces , glycolipid , weaning , excretion , cerebroside , medicine , physiology , biology , endocrinology , biochemistry , microbiology and biotechnology
Glycosphingolipids were shown to persist in human fecal excretions from birth up 2 years of age. The pattern of glycosphingolipids was dependent on blood group and secretor status of the child and changed dramatically during the first months of life. Perinatally cerebroside, hematoside and blood group active fucolipids were dominating among fecal glycolipids. From the time of weaning lactosylceramide abruptly became and then persisted as a dominating glycolipid although cerebroside, complex gangliosides and blood group active fucolipids could still be detected in feces even at 2 years of age.