Premium
1‐ O ‐Alkyl‐2‐acetyl‐ sn ‐glyceryl‐3‐phosphorylcholine (PAF) is a minor lipid component in Tetrahymena pyriformis cells
Author(s) -
Lekka Marilena,
Tselepis Alexandros D.,
Tsoukatos Demokritos
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)81530-7
Subject(s) - tetrahymena pyriformis , tetrahymena , extracellular , calcium , chemistry , ionophore , phosphorylcholine , zymosan , alkyl , biochemistry , in vitro , organic chemistry
The protozoan Tetrahymena pyriformis contains 4.2 ± 2.2 ng PAF/10 7 cells. Only 1–3% of this lipid is released in the cell free medium. PAF production is not influenced by different extracellular Ca 2+ concentrations. Cell stimulation with calcium ionophore A23187 or zymosan particles does not affect the amount of PAF either. This is the first report of a natural occurrence of PAF in a protozoan.