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Demonstration of mRNAs for oxytocin and prolactin in porcine granulosa and luteal cells
Author(s) -
Einspainer Ralf,
Pitzel Lutz,
Wuttke Wolfgang,
Hagendorff Gerd,
Preuß Klaus-Dieter,
Kardalinou Efterpi,
Scheit Karl Heinz
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)81383-7
Subject(s) - oxytocin , prolactin , luteal phase , medicine , endocrinology , corpus luteum , relaxin , secretion , hormone , chemistry , granulosa cell , ovary , biology
The relative levels of mRNAs for relaxin, prolactin, inhibin and oxytocin have been measured in porcine granulosa as well as luteal cells by hybridisation to single‐stranded synthetic DNA. The likelihood of a paracrine function of oxytocin and prolactin in the porcine ovary was inferred from the invitro effects of both both hormones on progesterone secretion of ovarian cells. Both hormones were found to inhibit progesterone secretion of luteal cells. In contrast, only prolactin but not oxytocin stimulated progesterone secretion in granulosa cells.