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A gene in Paracoccus for subunit III of cytochrome oxidase
Author(s) -
Saraste Matti,
Raitio Mirja,
Jalli Tuulikki,
Perämaa Anja
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)81359-x
Subject(s) - paracoccus denitrificans , cytochrome c oxidase , protein subunit , biology , biochemistry , cytochrome b , cytochrome c1 , open reading frame , gene , enzyme , microbiology and biotechnology , mitochondrial dna , peptide sequence
The region of Paracoccus denitrificans chromosome where the genes coding for cytochrome oxidase (cytochrome aa 3 ) subunits are located has been cloned. DNA sequencing revealed an open reading frame that codes for a protein homologous to the subunit III of the eukaryotic, mitochondrial enzyme. This subunit is absent from the isolated Paracoccus oxidase. It now seems that it is part of the native enzyme in the bacterial cytoplasmic membrane. This may explain the observed discrepancies in the function of the isolated enzyme.