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cDNA and protein sequence of the NC1 domain of the α 2 ‐chain of collagen IV and its comparison with α 1 (IV)
Author(s) -
Schwarz-Magdolen Ulla,
Oberbäumer Ilse,
Kühn Klaus
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)81018-3
Subject(s) - complementary dna , homology (biology) , peptide sequence , sequence (biology) , domain (mathematical analysis) , sequence homology , microbiology and biotechnology , genetics , amino acid , biology , chemistry , gene , mathematics , mathematical analysis
We present the complete cDNA and derived amino acid sequence of the non‐collagenous domain NCl of α 2 (IV). Comparison with the corresponding NC1 domain of α(IV) reveals a high degree of homology at the protein level in contrast to the barely homologous triple‐helical sequences of both chains.