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Complete cDNA sequence for rabbit muscle glycogen phosphorylase
Author(s) -
Nakano Kenichi,
Hwang Peter K.,
Fletterick Robert J.
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)80829-8
Subject(s) - glycogen phosphorylase , complementary dna , rabbit (cipher) , glycogen , sequence (biology) , biochemistry , glycogen synthase , glycogen debranching enzyme , phosphorylase kinase , chemistry , microbiology and biotechnology , biology , gene , computer science , computer security
The cDNA for the nearly full‐length rabbit muscle glycogen phosphorylase mRNA has been isolated and sequenced. The cDNA is rich in G and C nucleotides. This feature is especially striking at the 3rd position of codons, where 86% of the 843 amino acid codons terminate with G or C. Methionine, presumably the initiation residue, is found at position—1, suggesting that the removal of only a single methionine residue precedes the amino‐terminal acetylation at serine. Eight differences between the deduced amino acid sequence and the previously determined protein sequence are discussed.