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Sequence dependence and role of 5'‐phosphate in the B to Z transition
Author(s) -
Majumder Kumud,
Brahmachari Samir K.,
Sasisekharan V.
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)80413-6
Subject(s) - phosphate , transition (genetics) , sequence (biology) , chemistry , stereochemistry , crystallography , biochemistry , gene
Spectroscopic studies on pd(CG) 3 and pd(GC) 3 have been carried out to elucidate the sequence dependence and effect of free 5'‐phosphate on the B to Z transition. Unlike d(CG) 3 , pd(CG) 3 fails to undergo salt‐induced B to Z transition at ambient temperature. Model building studies have been carried out to determine the inhibitory role of the 5'‐phosphate group, but have been unsuccessful.