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Splicing pathways of the chicken apo very low density lipoprotein II (pre)messenger RNA
Author(s) -
Noteborn Mathieu,
Arnberg Annika,
de Jonge Martinus,
Geert A.B.,
Gruber Max
Publication year - 1986
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(86)80067-9
Subject(s) - intron , rna splicing , messenger rna , gene , group ii intron , microbiology and biotechnology , rna , precursor mrna , biology , chemistry , genetics
The precursor‐mRNA transcribed from the chicken apo very low density lipoprotein II gene was identified. This gene which is under full estrogen control and only expressed in the liver, possesses three introns. Splicing intermediates were characterized by hybridization with intron‐specific probes, and by electron microscopy of R‐loops. The introns appear to be excised in a non‐obligatory order, but at different rates.