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Parthenogenetic activation decreases the polyphosphoinositide content of frog eggs
Author(s) -
Le Peuch C.J.,
Picard A.,
Dorée M.
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)81214-x
Subject(s) - phosphatidylinositol , xenopus , oocyte activation , parthenogenesis , chemistry , phosphate , amphibian , oocyte , metaphase , biology , microbiology and biotechnology , biochemistry , ecology , phosphorylation , embryo , gene , chromosome
Polyphosphoinositides were quantified in metaphase II‐arrested eggs of the amphibian Xenopus laevis , and 8–10 min later in eggs activated by pricking. The content of phosphatidylinositol 4,5‐biphosphate (PIP 2 ) was remarkably high in metaphase II‐arrested eggs with respect to that of phosphatidylinositol 4‐phosphate (PIP). It was found to drop dramatically at activation. In contrast PIP content did not change significantly.