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A role for Ca 2+ in the effect of very low frequency electromagnetic field on the blastogenesis of human lymphocytes
Author(s) -
Conti P.,
Gigante G.E.,
Alesse E.,
Cifone M.G.,
Fieschi C.,
Reale M.,
Angeletti P.U.
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)81107-8
Subject(s) - verapamil , calcium , electromagnetic field , chemistry , lymphocyte , biophysics , medicine , microbiology and biotechnology , immunology , biology , physics , organic chemistry , quantum mechanics
The DNA synthesis of lymphocytes triggered by phytohemagglutinin or phorbol‐myristate‐acetate is strongly reduced by the externally applied electromagnetic field (ELF). Ca 2+ uptake by stimulated lymphocytes is also reduced by ELF. The effect appears to be synergistic with that of the well‐known calcium blocker agent, verapamil.