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Measurement of the sodium membrane potential by NMR
Author(s) -
Cowan Barrett E.,
Sze Daniel Y.,
Mai Michael T.,
Jardetzky Oleg
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)80668-2
Subject(s) - sodium , extracellular , chemistry , nuclear magnetic resonance , intracellular , isotopes of sodium , transmembrane protein , analytical chemistry (journal) , membrane , nuclear magnetic resonance spectroscopy , chromatography , biophysics , biochemistry , physics , stereochemistry , organic chemistry , biology , receptor
Using nuclear magnetic resonance (NMR), we have developed a method of noninvasively determining the transmembrane sodium potential in erythrocytes by measuring intracellular and extracellular sodium concentrations. The experimental values correlated well with values obtained from standard flame photometric methods.