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Changes in the size of isolated chromaffin granules in ATP‐evoked catecholamine release
Author(s) -
Warashina Akira
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)80659-1
Subject(s) - granule (geology) , catecholamine , chemistry , biophysics , chromaffin cell , adrenal medulla , chromatography , endocrinology , materials science , biology , composite material
The average size of chromaffin granules isolated from bovine adrenal medullae was analyzed by a quasielastic laser light scattering method. The granule diameter increased by a factor of 1.3 by addition of Mg‐ATP in the medium. The ATP effect was completely suppressed in the presence of an anion transport blocker (SITS), and partly depressed by a proton transport blocker (DCCD).