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A novel RNA digesting activity from commercial polynucleotide phosphorylase
Author(s) -
Labuda D.,
Nicoghosian K.,
Cedergren R.J.
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)80520-2
Subject(s) - polynucleotide phosphorylase , phosphodiester bond , rnase p , polynucleotide , rna , biochemistry , chemistry , enzyme , degradosome , purine nucleoside phosphorylase , purine , gene
RNase A 4 is a new RNase activity found as a contaminant in commercial polynucleotide phosphorylase. This enzyme has the ability of hydrolyzing the phosphodiester bond between pyrimidine‐A in both loop and paired regions of RNA.