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Discovery of a γ‐carboxyglutamic acid‐containing protein in human spermatozoa
Author(s) -
Soute Berry A.M.,
Müller-Esterl Werner,
de Boer-van den Berg Marian A.G.,
Ulrich Magda,
Vermeer Cees
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)80444-0
Subject(s) - chemistry , biochemistry
Here we describe the identification of a γ‐carboxyglutamic acid‐containing protein in human spermatozoa. After thermal decarboxylation the protein is a good substrate for vitamin K‐dependent carboxylase from various origins. A quick purification procedure for the decarboxylated protein is presented and in a preliminary characterization we have established its M r , (28000–30000) and its amino acid composition.