Premium
Ribosome ‐ SRP ‐ signal sequence interactions
Author(s) -
von Heijne Gunnar
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)80414-2
Subject(s) - sequence (biology) , signal (programming language) , computational biology , ribosome , signal recognition particle , signal peptide , biological system , chemistry , computer science , biology , biophysics , peptide sequence , biochemistry , rna , gene , programming language
The role of the signal sequence in protein export is reviewed, and some difficulties inherent in the conventional picture of how it interacts with other components of the export machinery are pointed out. An alternative model is suggested, which seems to account better for some of the critical experimental findings made so far.