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Reconstituted high density lipoprotein behaviour is modified by the nature of the lipid vesicle
Author(s) -
Jones Sheelagh M.A.,
Rogers M.Perenna
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)80232-5
Subject(s) - sphingomyelin , vesicle , phosphatidylcholine , chemistry , high density lipoprotein , lipoprotein lipase , lipoprotein , apolipoprotein b , cholesterol , biochemistry , low density lipoprotein receptor related protein 8 , hepatic lipase , enzyme , very low density lipoprotein , phospholipid , membrane
Apo HDL is a more potent inhibitor of lipoprotein lipase than native HDL. HDL reconstituted from apo HDL and vesicles made from either HDL total lipids or HDL phospholipids inhibits lipoprotein lipase in the same manner as native HDL. HDL reconstituted from apo HDL and vesicles made from phosphatidylcholine and sphingomyelin still behaves like apo HDL.