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Caldesmon‐induced inhibition of ATPase activity of actomyosin and contraction of skinned fibres of chicken gizzard smooth muscle
Author(s) -
Szpacenko A.,
Wagner J.,
Dabrowska R.,
Rüegg JC.
Publication year - 1985
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(85)80032-6
Subject(s) - gizzard , caldesmon , contraction (grammar) , biophysics , chemistry , actin , smooth muscle , muscle contraction , atpase , tropomyosin , anatomy , biochemistry , endocrinology , biology , calmodulin , enzyme , zoology
Caldesmon induces inhibition of MG 2+ ‐ATPase activity of actomyosin and relaxation of skinned fibers of chicken gizzard smooth muscle without influencing the level of myosin light chain‐1 phosphorylation. Both these effects are reversed by calmodulin at a high molar excess over caldesmon in the presence of Ca 2+ .