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Possible functional role of viral tRNA‐like structures
Author(s) -
Florentz C.,
Briand J.P.,
Giegé R.
Publication year - 1984
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(84)81183-7
Subject(s) - transfer rna , translation (biology) , rna , generalization , computational biology , biology , genetics , messenger rna , gene , mathematics , mathematical analysis
Although numerous hypotheses, reviewed here, have been proposed the functional role of viral tRNA‐like structures remains unknown. We describe and discuss a new model based on observations made mainly on TYMV RNA. By interacting with the tRNA‐like structure, valyl‐tRNA synthetase would allow an efficient translation of the viral genome. The generalization for other viral RNAs is proposed.