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Isozymes of glycogen synthase
Author(s) -
Kaslow Harvey R.,
Lesikar David D.
Publication year - 1984
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(84)81144-8
Subject(s) - isozyme , glycogen synthase , atp synthase , chemistry , glycogen branching enzyme , biochemistry , glycogen debranching enzyme , glycogen , enzyme
Antisera to rat skeletal muscle glycogen synthase failed to recognize liver glycogen synthase by electroblot analysis. The antisera recognized the enzyme in skeletal muscle, heart, fat, kidney, and brain. The results support the hypothesis that there are at least two isozymes of glycogen synthase, and that most tissues contain a form similar or identical to the skeletal muscle type. There is a virtual absence of the muscle‐type enzyme in adult rat liver.