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Decrease by glucagon in peroxide generation by isolated hepatocytes
Author(s) -
Siess E.A.,
Wieland O.H.
Publication year - 1984
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(84)80970-9
Subject(s) - glucagon , catalase , peroxide , chemistry , formate , biochemistry , catalysis , medicine , endocrinology , biology , enzyme , organic chemistry , hormone
Exposure of isolated rat liver cells to glucagon or dibutyryl cyclic AMP leads to a prompt decrease in the rate of cellular peroxide generation as evidenced by (i) a reduced rate of [ 14 C]formate oxidation and (ii) a lowered steady‐state concentration of catalase Compound I.