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Dictyostelium discoideum cell membranes contain masked chemotactic receptors for cyclic AMP
Author(s) -
Janssens P.M.W.,
van Driel R.
Publication year - 1984
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(84)80950-3
Subject(s) - dictyostelium discoideum , chemotaxis , receptor , membrane , dictyostelium , chemistry , microbiology and biotechnology , cell surface receptor , cell membrane , biochemistry , cell , molar concentration , biophysics , biology , organic chemistry , gene
Aggregating Dictyostelium discoideum cells possess highly specific receptors for the chemoattractant cAMP on their cell surface. Isolated membranes as well as intact cells are shown to contain a large number of latent cAMP receptors. These are reversibly unmasked in the presence of a high salt concentration (0.1–2 M) or in the presence of millimolar concentrations of Ca 2+ .