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Evidence from peptide mapping for a human renin zymogen
Author(s) -
McIntyre Gordon D.,
Chaudhuri Subhendu,
Coggins John R.
Publication year - 1984
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(84)80784-x
Subject(s) - zymogen , renin–angiotensin system , peptide , chemistry , biochemistry , enzyme , peptide mapping , sequence (biology) , peptide sequence , biology , endocrinology , gene , blood pressure
Data obtained from peptide mapping of the active and inactive forms of human renin show that there are extensive regions of common sequence in the two forms of the enzyme, and are consistent with the hypothesis that inactive renin is a renin zymogen.