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Prediction structure type for human leukocyte Interferon subtype A from circular dichroism
Author(s) -
Manavalan P.,
Johnson W.Curtis,
Johnston Paul D.
Publication year - 1984
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(84)80741-3
Subject(s) - antiparallel (mathematics) , circular dichroism , protein secondary structure , beta sheet , protein tertiary structure , chemistry , protein structure , crystallography , physics , biochemistry , quantum mechanics , magnetic field
Vacuum UV circular dichroism studies were carried out on human leukocyte interferon subtype A. The secondary structure analysis for the CD spectrum shows 59% α‐helix, 16% antiparallel β‐sheet, no parallel β‐sheet, 18% β‐turns and 13% other structures. The analysis of the CD features for the prediction of tertiary structural class reveals that it is an all‐α type protein.