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Hemoglobin Aichi [α50(CE8) His → Arg]: a new slightly unstable hemoglobin variant discovered in Japan
Author(s) -
Harano Teruo,
Harano Keiko,
Shibata Susumu,
Ueda Satoshi,
Mori Hiroo,
Seki Masami
Publication year - 1984
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(84)80337-3
Subject(s) - hemoglobin , hemoglobin s , hemoglobin variants , chemistry , oxygen , biochemistry , cell , sickle cell anemia , organic chemistry
A new abnormal hemoglobin, Hb Aichi [α50(CE8) His → Arg], was discovered in a young Japanese man. This variant was isoelectrofocussed between Hb A and Hb A 2 and amounted to about 21% of the total hemoglobin in the hemolysate. This hemoglobin showed normal oxygen affinity but slight instability.