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Characterization of the permeability increase induced by the incorporation of glycophorin in phosphatidylcholine vesicles
Author(s) -
van Hoogevest Peter,
du Maine Atala P.M.,
de Kruijff Ben
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)81112-0
Subject(s) - glycophorin , vesicle , chemistry , phosphatidylcholine , biophysics , permeability (electromagnetism) , bilayer , lipid bilayer , lipid vesicle , chromatography , membrane , phospholipid , biochemistry , biology
Glycophorin incorporation into large unilamellar dioleoylphosphatidylcholine vesicles results in a greatly increased bilayer permeability for non‐electrolytes of M r ‐values up to 900. This suggests that glycophorin aggregates induce the formation of pores with a 15–18 Å diameter.