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Reduced mitogenic stimulation of human lymphocytes by extremely low frequency electromagnetic fields
Author(s) -
Conti Pio,
Gigante Giovanni Ettore,
Cifone Maria Grazia,
Alesse Edoardo,
Ianni Gianfranco,
Reale Marcella,
Angeletti Pietro Ubaldo
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)81069-2
Subject(s) - stimulation , electromagnetic field , chemistry , microbiology and biotechnology , physics , biophysics , biology , neuroscience , quantum mechanics
Blastogenesis of human peripheral blood lymphocytes stimulated in vitro by non‐specific mitogens (PHA, ConA, PWM) upon exposure to extremely low frequency EMF has been studied. Different frequencies of square waveforms have been used. PHA‐stimulation resulted in strong inhibitions as measured by [ 3 H]thymidine incorporation. A frequency window (3–50 Hz) within which ConA‐induced blastogenesis was significantly inhibited has been individuated. The mitogenic effect of PWM was significantly affected only at 3 Hz.