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Template‐independent synthesis of guanosine tetra‐ and pentaphosphates on ribosomes
Author(s) -
Belitsidezhda V.,
Klyachko Elena V.,
Shakulov Rustem S.
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)81044-8
Subject(s) - ribosome , transfer rna , guanosine , escherichia coli , chemistry , stringent response , biochemistry , stereochemistry , rna , gene
It is shown that Escherichia coli ribosomes carrying poly(Lys)‐tRNA can form (p)ppGpp in the presence of stringent factor in the absence of the poly(A) template. Template‐independent synthesis of (p)ppGpp is suppressed by tetracycline and partially decreases if deacylated tRNA is omitted.