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Classification of tropomyosin components into an α‐like or a β‐like family by partial peptide mapping
Author(s) -
Kardami Elissavet,
Fiszman Marc-Yves
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80829-1
Subject(s) - tropomyosin , gizzard , peptide , molecular mass , biochemistry , chemistry , biology , microbiology and biotechnology , actin , enzyme , paleontology
Tropomyosins can be classified as belonging to an α‐like or a β‐like family depending on the absence or presence, respectively, in their protease‐V8 digestion pattern of two peptides with an apparent molecular mass of 21 kDa. Chicken cardiac tropomyosin and the 43 kDa component from gizzard tropomyosin are accordingly classified as α‐like tropomyosins, while the 33 kDa gizzard tropomyosin component is a β‐like tropomyosin. The 21 kDa peptides have an overall charge which is more positive than that of the intact tropomyosin or any other tropomyosin peptide and probably contain the ‐NH 2 half of the molecule.