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The effects of mutations, deletions and insertions of single amino acids on the three‐dimensional structure of globins
Author(s) -
Kolchanov N.A.,
Soloviov V.V.,
Zharkikh A.A.
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80731-5
Subject(s) - myoglobin , globin , amino acid , sperm whale , genetics , mutation , biology , chemistry , gene , microbiology and biotechnology , biochemistry
Using the method of calculation of low energy packings of α‐helices, we studied the effects of mutations, deletions and insertions of amino acids on the structure of sperm whale myoglobin. It was found that these events can cause complete breakdown of this structure.