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The ratio between intrinsic 115 kDa and 30 kDa peptides as a marker of fibre type‐specific sarcoplasmic reticulum in mammalian muscles
Author(s) -
Wiehrer Walter,
Pette Dirk
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80604-8
Subject(s) - endoplasmic reticulum , chemistry , stimulation , atpase , biophysics , sarcoplasm , membrane , biochemistry , microbiology and biotechnology , biology , endocrinology , enzyme
Sarcoplasmic reticulum displays characteristic differences in Ca 2+ ‐uptake, Ca 2+ ‐ATPase and the pattern of membrane proteins in type I, IIA and IIB fibres. The ratio between the 115 kDa Ca 2+ ‐ATPase and a 30 kDa protein is of characteristic magnitude in the sarcoplasmic reticulum of the three fibre types in rat muscles. The slow‐to‐fast fibre type transformation observed in rabbits during chronic nerve stimulation is accompanied by predictable changes of this ratio.