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Epoxide hydrolase activity in isolated peroxisomes of mouse liver
Author(s) -
Waechter Felix,
Philip Bentley,
Françoise Bieri,
Willy Stäubli,
Alfred Völkl,
Fahimi Hussein D.
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80583-3
Subject(s) - peroxisome , epoxide hydrolase , organelle , biochemistry , cytosol , substrate (aquarium) , chemistry , mitochondrion , microsome , enzyme , biology , ecology , gene
Using trans ‐stilbene oxide as substrate, the subcellular distribution of epoxide hydrolase was investigated in livers from DBA/2 mice. The highest specific activities were found in cytosolic and light mitochondrial fractions. Isopycnic subfractionation of the light mitochondrial fraction showed that the organelle‐bound trans ‐stilbene oxide hydrolase is localized in peroxisomes.