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An estimate of the dipole moment of superoxide dismutase
Author(s) -
Leeuwen Johan W.van
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80509-2
Subject(s) - superoxide dismutase , debye , dipole , moment (physics) , superoxide , chemistry , limit (mathematics) , ionic strength , nuclear magnetic resonance , enzyme , biochemistry , physics , mathematics , quantum mechanics , mathematical analysis , organic chemistry , aqueous solution
A lower limit for the value of the dipole moment of superoxide dismutase (SOD) is calculated to be 485 Debye. This limit follows from the observation that the rate constant of the reaction between superoxide (O − 2 ) and SOD decreases upon increasing the ionic strength, and the fact that at pH > 5 SOD has a net negative charge.