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A radioimmunoassay for the Hydra head activator
Author(s) -
Bodenmüller Heinz,
Zachmann Beate
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80454-2
Subject(s) - radioimmunoassay , activator (genetics) , lernaean hydra , antiserum , chemistry , enzyme , microbiology and biotechnology , biochemistry , chromatography , biology , antigen , immunology , receptor
A highly sensitive and specific radioimmunoassay for the head activator has been developed which utilises tritriated head activator. The assay is sensitive in the range of 40–200 fmol. Immunochemical studies showed that the antiserum recognised the intact molecule better than any of the fragments or derivatives produced by enzymatic treatment or chemical synthesis.