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Increase of the glycolytic rate in human resting fibroblasts following serum stimulation
Author(s) -
Bruni Paola,
Farnararo Marta,
Vasta Valeria,
D'Alessandro Antonino
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80412-8
Subject(s) - stimulation , glycolysis , endocrinology , medicine , chemistry , metabolism , biology
We report that glycolysis in human quiescent fibroblasts stimulated by serum addition is increased, and that the changes of the metabolic route reflect the activity of the phosphofructokinase. A possible role of fructose‐2,6‐bisphosphate as a positive modulator of the key enzyme is proposed.