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Enzymatic synthesis of a blood group A related, difucosyl heptaglycosylceramide with a type 2 carbohydrate chain
Author(s) -
Samuelsson Bo E.
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80401-3
Subject(s) - fucosyltransferase , carbohydrate , enzyme , chemistry , blood type (non human) , abo blood group system , biochemistry , in vitro , group a , stereochemistry , biology , medicine , immunology
The presence of an α1→3 fucosyltransferase in the serum of an A 1 Rh(−) Le(a−b+) Fy(a−b+) Jk(a+b+)K(−)M(−)N(+)S(−)s(+)P 1 (+) human secretor was shown, capable of converting a blood group A active hexaglycosylceramide with a type 2 carbohydrate chain into the corresponding difucosyl compound under in vitro conditions.