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Isoproterenol stimulates lipid methylation in C 6 cells without affecting membrane fluidity
Author(s) -
McKenzie Roderick C.,
Brophy Peter J.
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80294-4
Subject(s) - membrane fluidity , methylation , chemistry , biophysics , lipid accumulation , membrane , microbiology and biotechnology , biochemistry , biology , gene
C 6 glioma cells stimulated with the β‐adrenergic agonist isoproterenol. The rate of cyclic AMP accumulation and lipid methylation increased. However, the elevated rate of lipid methylation did not affect the fluidity of the plasma membrane. It is concluded that lipid methylation is not responsible for making the plasma membrane more fluid during the β‐adrenergic response.