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Stretches of alternating poly(T‐dG), with the capacity to form Z‐DNA, are present in human liver transcripts
Author(s) -
Santoro C.,
Costanzo F.
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80211-7
Subject(s) - complementary dna , polyadenylation , dna , microbiology and biotechnology , cdna library , human liver , southern blot , rna , sequence (biology) , northern blot , nucleic acid sequence , dot blot , clone (java method) , biology , gene , genetics , in vitro
A cDNA clone consisting of a stretch of poly(T—dG) alternating residues, a potential Z‐DNA forming sequence, was identified in a human cDNA library. The result of Northern blot analysis confirms that this sequence is transcribed into polyadenylated RNA in human liver.