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Erythrocuprein (Cu 2 Zn 2 superoxide dismutase) is the major copper protein of the red blood cell
Author(s) -
Gärtner Alfred,
Weser Ulrich
Publication year - 1983
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(83)80199-9
Subject(s) - copper , superoxide dismutase , chemistry , dismutase , zinc , red blood cell , biochemistry , nuclear chemistry , enzyme , organic chemistry
The copper balance in the red blood cell deserved special attention as the exact amount of copper being bound in erythrocuprein (Cu 2 Zn 2 superoxide dismutase) is poorly understood. An improved aqueous isolation of erythrocuprein revealed that essentially all erythrocyte copper is found in this protein. This fact is supported by both superoxide dismutase activity measurements of the haemolysate and EPR‐quantification studies throughout the course of the isolation.