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A new silent hemoglobin variant in a black family from French West Indies
Author(s) -
Sellaye M.,
Blouquit Y.,
Galacteros F.,
Arous N.,
Monplaisir N.,
Rhoda M.D.,
Braconnier F.,
Rosa J.
Publication year - 1982
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(82)81220-9
Subject(s) - martinique , west indies , isoelectric focusing , hemoglobin , cord blood , biology , biochemistry , genetics , history , ethnology , enzyme
A new abnormal hemoglobin Hb Le Lamentin α20 (B1) His→Gln was discovered during a survey of cord blood from the French West Indies (Martinique). This variant displays an electrophoretic pattern similar to that of Hb A but can be isolated by isoelectric focusing (IEF) and Biorex 70 chromatography. Family studies showed the presence of this hemoglobin variant in the father and in two of his three children. Hematological data from the carriers were normal.