Premium
Activation of human and mouse 2‐5A synthetases and mouse protein P 1 kinase by nucleic acids
Author(s) -
Torrence Paul F.,
Johnston Margaret I.,
Epstein David A.,
Jacobsen Helmut,
Friedman Robert M.
Publication year - 1981
Publication title -
febs letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.593
H-Index - 257
eISSN - 1873-3468
pISSN - 0014-5793
DOI - 10.1016/0014-5793(81)81142-8
Subject(s) - diabetes mellitus , gerontology , medicine , national laboratory , chemistry , library science , endocrinology , physics , engineering physics , computer science
The natural occurrence of fully double-stranded RNA (dsRNA) of high molecular weight in viruses, virus-like particles in fungi, as intermediates in the replication of RNA and DNA viruses has suggested some possible biological role for such molecules [ 11. Interest in dsRNA as a possible regulatory signal has been generated by the observations that dsRNA is a potent interferon inducer [2] and a powerful inhibitor